We study all things glia!

Glial Tiling

Glial-Glial Interactions

Glial Cell Development

Glial Diversity

Glial-Mediated Debris Clearance

Regeneration

In the Kucenas Lab, we are fascinated by the cellular and molecular mechanisms that drive glial development. We historically have studied how glia engineer neural development via glial-glial and neural-glial interactions. Using zebrafish (Danio rerio), coupled with genetic and pharmacological perturbation, single cell manipulation, laser ablation, small molecule screening, single-cell RNA-sequencing (scRNAseq), proximity proteomics, and in vivo, time-lapse imaging, we have discovered novel glial populations, revealed how glia communicate in several unique contexts, and created many new tools for our studies and the broader community. Our approach to science is to “chase the weird” and continue to reveal the complex and essential roles of all things glia!


See our Projects page for more details!